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Long-Term Affordability The benefits of GLP-1s far outweigh the adverse effects for the majority of people living with type 2 diabetes or obesity
This gives new hope to people looking for weight loss treatments
People should not attempt to take the drugs by other means, for instance, through being "prescribed by the internet without any guidance or supervision." Patients should also know the potential side effects, and understand what measures can be taken to mitigate them
The GLP-1 space really took off with semaglutide: first as Ozempic for type 2 diabetes in 2017, then as Wegovy for obesity in 2021
![Efficacy of tirzepatide in phase 2 (GPGB; [14]) and phase 3 (SURPASS-1](https://www.researchgate.net/publication/363201315/figure/fig3/AS:11431281082605778@1662084799021/Efficacy-of-tirzepatide-in-phase-2-GPGB-14-and-phase-3-SURPASS-1-to-5-15-19.png)
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