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Vitamin B12 deficiency has been tied to the genetics of various populations, which can affect the pathways of uptake and metabolism
10.2337/db20-0921 82 LbbanE.MaceyA.RundleJ.AshorA.IdrisI.SiervoM
Because the heart muscle derives the vast majority of its energy from the beta-oxidation of fatty acids, a depletion of L-Carnitine severely compromises the heart's ability to sustain this compensatory effort
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