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Moreover, combination therapies have demonstrated significant advantages, such as Novo Nordisks CagriSema (semaglutide + cagrilintide), which shows superior glycemic control and weight reduction effects compared to semaglutide alone, demonstrating that combination therapy can achieve more than the sum of its parts while reducing side effects
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Evidence level: Level C (observational comparative) suggests no increased infection liability and possible reduced risk vs SGLT2 inhibitors
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