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The Science: Why Refrigeration is Non-Negotiable Tirzepatide is a peptide, a complex molecule made of amino acids
After its promising effects on biomarkers in a phase 2 trial on AD [155], a phase 2a study in patients with mild-to-moderate dementia with Lewy bodies (DLB) showed a favourable safety profile as well as reversal of pathology in a BFCN degeneration mouse model [154]
[1] [8] The combined stimulation of these three pathways is intended to create a synergistic effect on appetite suppression, caloric intake reduction, and metabolic rate
In addition to profoundly compromising quality of life and daily functioning, this disorder contributes to the pathogenesis of numerous chronic diseasesincluding hypertension, coronary artery disease, stroke, diabetes, and cognitive impairmentand has been correlated with elevated all-cause mortality risk (46)
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