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However, after oral or systemic administration, Dex lacks organ-targeting capabilities, so higher doses and frequencies are required to achieve effective concentrations at the site of inflammation [103], which causes severe side effects on the hematological and alimentary systems [104]
Ozempic is contraindicated in patients with a personal or family history of MTC or in patients with multiple endocrine neoplasia syndrome type 2 (MEN 2)
Wegovy received FDA approval in 2024 to reduce the risk of heart attack, stroke, and cardiovascular death in overweight or obese adults with established heart disease
GLP-1 side effects, like nausea, can also make people drink less water
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