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Clinical Evidence on GLP-1 and Oral Contraceptive Interaction Direct clinical trials specifically measuring birth control efficacy during GLP-1 therapy remain sparse
[10] Valproate is restricted in the United Kingdom for both women and men under age 55 due to teratogenicity in pregnant women and fertility problems in men
This is one area where the long-term benefits of semaglutide may actually outweigh the short-term indirect risks from side effects
Another key consideration is side effects, which can vary significantly from patient to patient
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