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Progesterone is the major female reproductive hormone, especially during the latter 2 weeks of the monthly menstrual cycle, where it is made by a part of the ovary called the corpus luteum

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The mucus layer in the colon is thicker, compared with the small intestine where pore size ranges from 4 to 5 at the villus tip to over 20 at the base of the crypt [5]

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