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They mimic natural GLP-1 but resist rapid breakdown by the enzyme DPP-4, providing sustained activity

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Semaglutide supports weight loss by helping the body regulate appetite and digestion: Mimics a natural GLP-1 hormone that helps control hunger Signals the brain to feel full sooner and longer Slows digestion to help reduce overeating Decreases food cravings and snacking Supports steady, controlled weight loss over time Semaglutide works best when combined with healthy nutrition, movement, and ongoing medical supervision

However, the estimate of the modified intention-to-treat analysis was not substantially different from that of the main analysis