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This is largely controlled by a RING finger E3 ligase, MDM2 (murine double minute 2, HDM2 in human) 49
The peptide's short half-life and mechanism of action create specific timing considerations that can make or break your results
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Moonens K, Gideonsson P, Subedi S, Bugaytsova J, Roma E, Mendez M, Nordn J, Fallah M, Rakhimova L, Shevtsova A, Lahmann M, Castaldo G, Brnnstrm K, Coppens F, Lo AW, Ny T, Solnick JV, Vandenbussche G, Oscarson S, Hammarstrm L, Arnqvist A, Berg DE, Muyldermans S, Born T, Remaut H (2016) Structural insights into polymorphic ABO glycan binding by Helicobacter pylori
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