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To address this therapeutic gap, we have developed MEDI4166, a novel glucagon-like peptide-1 (GLP-1) receptor agonist peptide fused to a proprotein convertase subtilisin/kexin type 9 (PCSK9) neutralising antibody that allows for glycaemic control and low-density lipoprotein cholesterol (LDL-C) lowering in a single molecule
As other members of the SLC22 family, OCTN2 can mediate cellular uptake of oxaliplatin and other chemotherapeutic agents (Jong et al., 2011
We next performed annexin V and Hoechst staining after incubated with indicated treatment for 17 hr to specifically determine the proportion of cell apoptosis
^ 6.0 6.1 Glutathione Metabolism and its Implications for Health
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