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The EBPBA structure was confirmed by 1 H NMR and ESI-MS (Supplementary Figs
The bio-availability of the DPP-4 inhibitors is very good and the pharmacodynamic- as well as the pharmacokinetic characteristics lead to the above mentioned clinically sufficient DPP-4 inhibition with once daily dosing (only vildagliptin has to be dosed twice daily) (18, 19)
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Los pacientes tratados presentaron menos ansiedad, insomnio y malestar, y pudieron superar la fase aguda de retirada con mayor comodidad
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