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Hydroxocobalamin may also be given intravenously in certain scenarios (for example, 5 g IV for acute cyanide poisoning antidote therapy), but such high-dose use is in emergency settings and distinct from routine deficiency treatment
Adding 2ml creates a concentration of 5mg/ml
To achieve equivalent systemic levels, nasal spray users need to administer proportionally higher doses
This method especially benefits individuals with compromised gastrointestinal health, as they may struggle to absorb B12 through food or oral supplements
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