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Effect of linagliptin vs placebo on major cardiovascular events in adults with type 2 diabetes and high cardiovascular and renal risk: the carmelina randomized clinical trial

However, the drink plenty of water caveat is crucial, as dehydration can exacerbate constipation from GLP-1 drugs, especially with the appetite-suppressing effects potentially leading to reduced fluid intake for those taking GLP-1 for weight management