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William Blair views the HbA1c lowering as competitive to 14 mg of Novos Rybelsus (semaglutide), which demonstrated up to 1.64% reduction in a subset of Chinese patients for its Phase 3 program

angiotensin IV analogue Sequence (formal name): N-hexanoic-Tyr-Ile-(6) aminohexanoic amide IUPAC name: 6-[(2S,3S)-2-[(2S)-2-hexanamido-3-(4-hydroxyphenyl)propanamido]-3-methylpentanamido]hexanamide Synonyms: PNB-0408, Hexanoyl-Tyr-Ile-Ahx-NH 2 , MM-201 (older designation) CAS Number: 1401708-83-5 Molecular Formula: C 27 H 44 N 4 O 5 Molecular Weight: 504.66 g/mol Solubility: slightly soluble in DMSO and methanol

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doi: 10.1016/j.tem.2024.05.002 Summary Keywords food preferences, gastrointestinal hormones, glucagon-like peptide 1, gut-brain axis, obesity, taste, taste receptors Citation Doval-Caballero JLE, Ferreira-Hermosillo A, Eugenio-Ponce GD, Garca-Senz MR, Ibarra-Salce R, Tenorio-Rojo AP, Luna-Avila ES, Gete-Palacios PC, Prez-Hernndez F, Rojas-Miln E, Lpez-Cruz LA and Mndez-Hernndez CA (2026) Potential role of glucagon like peptide 1 in taste receptors