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Weeks 24 First Phenotypic Signals In the DIO mouse study (Billon et al., J Biol Chem 2023, PMID 37739806), measurable weight and adiposity changes appeared in the first 2 weeks of 25 mg/kg IP BID dosing and accelerated through week 4
It is worth noting that patients with mUPD are more likely to have GHD compared to those with deletions (80% versus 25%) (100, 107109)
Purines are broken down into uric acid which is passed in urine
If you know you're allergic to benzyl alcohol, bacteriostatic water is not the right diluent for you
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