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In addition, studies on genetic susceptibility, neuroimaging indicators, and the metabolic - mood interaction mechanisms are expected to explain why some individuals are more sensitive to the mood effects of GLP 1RAs
doi: 10.1371/journal.pone.0142164 251 UngerMMSpiegelJDillmannKUGrundmannDPhilippeitHBrmannJet al
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51 As GSH is known to be present in CSF at very low concentrations (~0.2 mol/l in both healthy and PD subjects), 52 relative to brain tissue concentrations (~1 mmol/l), 7 LCModel-calculated Cr concentrations ( C measured ) were corrected ( C corrected ) using the following formula, which assumes negligible contribution of CSF GSH to the total GSH signal: Absolute GSH levels (IU) were calculated by multiplying GSH/Cr ratios by CSF-corrected absolute Cr concentrations (IU)
