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Taken together, drugs such as rifampicin, methotrexate, toosendanin, and triptolide induce liver damage through ferritinophagy- or lipophagy-dependent ferroptosis
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Exenatide has been used against LNCaP, PC3, and DU145 cell lines and showed some significant effect on PCa tumor progression [78, 92]
Early-phase clinical trial data, including results from a Phase 2 randomised controlled trial published in The New England Journal of Medicine in 2023 (Jastreboff et al., NEJM 2023), demonstrated significant weight reduction in adults with obesity (without type 2 diabetes), with participants receiving the highest dose losing a mean of approximately 24% of their body weight over 48 weeks
