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Song BJ, Moon KH, Upreti VV, Eddington ND, Lee IJ (2010) Mechanisms of MDMA (Ecstasy)-induced oxidative stress, mitochondrial dysfunction, and organ damage

it primarily affects motor function due to the loss of dopamine-producing neurons in the substantia nigra, a region of the midbrain

Eur J Clin Pharmacol 50:45761 Herzenberg LA, De Rosa SC, Dubs JG, Roederer M, Anderson MT, Ela SW, Deresinski SC, Herzenberg LA (1997) Glutathione deficiency is associated with impaired survival in HIV disease