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One case series (Fiaova et al., Endocrine Practice , 2024) reported 8 unplanned pregnancies in 340 women treated with GLP-1 agonists for weight loss, all in women with prior PCOS diagnoses who believed they had low fertility
In the clinical trials, visceral fat began to increase again once subjects stopped tesamorelin
However, maintaining long-term adherence to the drugs has been challenging
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