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The use of isotretinoin in acne
Current strategies to target G-protein-coupled receptors (GPR 40, GPR 119 and GPR 120) on intestinal L cells have shown theoretical potential for diabetes therapy, but the compounds that were effective were not safe enough [8]
Participants were randomized to placebo or retatrutide at 1 mg, 4 mg (dose-escalation), 4 mg (no escalation), 8 mg (escalation), 8 mg (no escalation), or 12 mg (escalation) for 48 weeks, following a slow titration protocol
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