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GLP-1 medications can help by reducing appetite and cravings, making it easier to maintain the calorie deficit needed for fat loss

GLP-1 RAs: From Rare to Routine GLP-1 RA are increasingly prescribed and recognized as therapeutics for metabolic health and cardiovascular health, with benefits that extend beyond weight loss

Thus, in perfect agreement with the recent ADA-EASD consensus report [6], we also encourage the adoption of GLP-1RA plus SGLT2i combination therapy in T2DM patients with established ASCVD (coronary artery disease, cerebrovascular disease, or peripheral arterial disease) or multiple risk factors for ASCVD (i.e., age 55 years, obesity, dyslipidemia, hypertension, current tobacco use, left ventricular hypertrophy, and/or proteinuria) whose HbA1c remains suboptimal despite initial treatment with only one of these agents