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Yes, there have been numerous studies about the side effects of GLP-1 medications like semaglutide, and some have not found any direct evidence that these medications cause acne, and others show a higher risk for acne in women
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Sethi BK, Viswanathan V, Kumar A, et al
This is usually a consequence of frequent or long term activation due to ongoing infections, allergic reactions or toxin exposure or even chronic stress i.e
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