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These include: Lifestyle interventions (dietary advice, physical activity programmes) Licensed pharmacotherapy such as orlistat, or GLP-1 receptor agonists including semaglutide 2.4 mg (Wegovy, NICE TA875) or tirzepatide (Zepbound) where clinically indicated and available Referral to tier 3 or tier 4 weight management services , including bariatric surgery assessment where appropriate Information on NHS weight management services and eligibility for licensed treatments is available via the NHS website and NICE guidance
This staged approach mirrors the evidence base for injectable fat reduction more widely
They want ingredients that can be explained, researched, and connected to real skin biology
It is important to note that Mounjaro is intended for adults with obesity or overweight and who have at least one weight-related health condition, such as hypertension or type 2 diabetes
