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How peptide immunotherapy achieves tolerance The mechanisms include induction of specific T-cell anergy (functional inactivation of allergen-reactive T-cells), differentiation of naive T-cells into regulatory T-cells, immune deviation (shifting the Th2/Th1 ratio toward Th1), and allergen-specific Th2 cell deletion

The zDHHC17 and 23 were PCR-amplified from the corresponding pEF-Bos-HA plasmids, cut with BglII/HindIII and inserted into the same sites of mRFP-KASH

Mice treated with Semaglutide significantly outperformed untreated APP/PS1 mice in building nests, suggesting enhanced abilities in daily activities

10.1093/humupd/dmy026 64 PepeG.SfogliariniC.RizzelloL.BattagliaG.PinnaC.RovatiG.et al (2021)