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This is due to the reduced incidence of prediabetes in patients with obesity [37, 46, 47] and improved markers for ovarian function in patients with obesity and PCOS [66], compared with placebo

Funding The research was supported in part by Grants-in-Aid for Challenging Exploratory Research and Scientific Research (B) from the Japan Society for the Promotion of Science (JSPS KAKENHI Grant Numbers JP26660218, JP21H02347, and JP24K01911, respectively) and by grant funds from the Uehara Memorial Foundation and Ito Foundation (all to R

doi: 10.1016/j.jfca.2021.104234 199