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Instead, PT-141 acts directly on the nervous system , particularly by activating melanocortin receptors in the brain
GLP-1 receptors are found not only in the gut and pancreas but also in key brain regions involved in reward, impulse control, and motivation
Study findings The study cohort consisted of 36,082 and 234,028 GLP-1 receptor agonist and DPP-4 inhibitor users, respectively, who were followed for a median of 1.3 and 1.7 years
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