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Effect of exenatide QW or placebo, both added to titrated insulin glargine, in uncontrolled type 2 diabetes: The DURATION-7 randomized study
However, patients who've established sustainable eating and exercise patterns often maintain much of their weight loss even after discontinuing medication
GLP-1 agonists slow down your digestive system, thus reducing hunger and making you feel fuller faster, however, that favorable mechanism comes with some gastrointestinal side effects
Therefore, both metformin and topiramate may play a role in the behavioral control of hyperphagia but without contributing to weight loss
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