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Loose skin poses a real concern if you are experiencing rapid weight loss with GLP-1 drugs: sagging skin can be uncomfortable, affect how clothing fits, cause skin irritation, and even pose a hygiene problem

If youre using GLP-1s for diabetes management: HbA1c and fasting glucose are primary markers Kidney function is monitored more closely, especially if you take metformin or insulin Lipids help track cardiovascular risk If youre using GLP-1s primarily for weight loss: Baseline metabolic labs still matter Liver enzymes and kidney function help track safety Blood sugar markers may be checked less frequently if you dont have diabetes In both cases, testing is most useful because it informs decisions, and empowers the user to own their health

On the other hand, some concerns to think about for older adults taking GLP-1s include: Dehydration

Some reviewers report significant weight loss results, with several mentioning losses of 25 to 30 pounds within the first three months of treatment