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Therefore, the production of ATP from fatty acid oxidation rather than low-yield anaerobic pathways or protein breakdown preserves body mass, muscle mass and muscle function under stress conditions [34, 35]

The activated forms of mTOR and S6K1 are localized mainly in the paraventricular and arcuate nuclei [119], being co-localized in a high percentage of orexigenic neurons that express AgRP/NPY and also in around half the anorexigenic neurons that express POMC/CART in the arcuate nuclei [119]

Liu et al 13 emphasized the disproportionate impact of these agents on patients of color and the importance of regulating their use