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Kupferminc MJ
The PYCR2 gene is located on chromosome 1q42.12 and is composed of 7 exons that generate two alternatively spliced mRNAs that encode proteins of 320 amino acids (isoform 1) and 246 amino acids (isoform 2)
It possesses strong oxidative properties and can react with reductive substances or biomolecules within the cell, thereby regulating redox reactions and influencing the expression of intracellular signaling molecules [45]
Acidosis drives the reprogramming of fatty acid metabolism in cancer cells through changes in mitochondrial and histone acetylation
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