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Reported phase 1b and phase 2 data describe dose-ranging pharmacokinetic and pharmacodynamic profiles, while structural biology studies have begun to map its binding mode across the three class B GPCRs

12 The REWIND trial evaluated dulaglutide in a broader population, including those with a lower baseline cardiovascular risk, and demonstrated a significant reduction in composite cardiovascular outcomes, together with a favourable trend in HF-related events

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