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This resulted in reduced WAT mass, increased liver mass, impaired glucose tolerance and elevated circulating FAs, which is consistent with a primary defect in adipose lipid storage
A further decrease (~ 43.3%) was observed following pretreatment with chlorpromazine hydrochloride, suggesting that clathrin-mediated endocytosis plays a significant role in the cellular internalization of SSPH-MPN
However, obesity is associated with more active Crohns disease
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