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Preclinical research suggested that simultaneous activation of both pathways might produce complementary metabolic benefits
Which medication offers the highest weight loss potential
In Danio rerio (zebrafish), ibuprofen increased oxidative stress markers, including catalase, glutathione S-transferase, and protein carbonyls (Falfushynska et al., 2022)
Greater reductions in HbA 1c and BP were also observed with tirzepatide, further supporting its metabolic benefits beyond weight loss
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