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In contrast, another demonstrated that macrophages, during the efferocytosis process, present a transient increase in glycolysis ( ~ 1h-6h), that is dependent on rapid post-translational mechanisms with increased expression of GLUT1 on the cell surface and glucose uptake, in a process that involves the activation of the glycolytic enzyme fructose-2,6-bisphosphatase 2 (PFKFB2)

Nakamura M et al

Payers and clinicians alike are beginning to treat obesity as a primary, chronic condition rather than a comorbidity, signaling a major shift in market dynamics

You can take it whenever it fits best into your routine without worrying that your morning coffee or evening snack is "ruining" your supplement's efficacy