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Retatrutide (LY3437943) is an investigational peptide developed by Eli Lilly that activates three hormone receptors simultaneously: GLP-1 receptor GIP receptor Glucagon receptor This is why retatrutide is often called a triple agonist. Most currently approved obesity medications target only one or two of these pathways

In one study, mice treated with 20mg/kg of 5-amino-1mq three times daily for 11 days experienced a 5.1% reduction in body weight from baseline

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