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Semaglutide mimics a hormone that our bodys naturally make known as glucagon-like peptide-1 (GLP-1)

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It is important to note that organelle-containing erythroid lineage cells can undergo intrinsic [37] and extrinsic apoptosis [38], receptor-interacting serine/threonine-protein kinase 1 (RIPK1)-dependent necroptosis [39], or iron-driven ferroptosis [40]

We did not include individuals treated with insulin alone as an active comparator as it would introduce a significant amount of bias with the lack of a codable index event (i.e