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These medications are typically considered when metformin and other treatments haven't achieved adequate glycaemic control, and are usually prescribed within a specific therapy sequence

We created a propensity score to match GLP1-RA users and DDP4i users at a ratio of 1:1 using 120 characteristics selected a priori (listed in Table 1), Variables included: age, gender (self-reported), race and ethnicity (self-reported), demographics, personal history, vital signs, comorbidities, comorbidity and cardiovascular scores, frailty score, healthcare utilization, laboratory values, glucose-lowering medication classes, and other medication classes

The body needs three to four weeks to establish a new steady state on the split schedule

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