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It plays a key role in: Neutralising free radicals Supporting liver detoxification Protecting skin cells from oxidative damage Maintaining even skin tone and clarity However, factors like pollution, stress, aging, poor diet, and UV exposure can reduce glutathione levels which is why supplementation is often recommended

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It differs from the native 70 residue growth factor in two respects: glutamate at position 3 is replaced by arginine, and a hydrophobic 13 residue extension (MFPAMPLLSLFVN) is fused to the N-terminus

Therefore, inhibiting lipid peroxidation may be a potential strategy for treating diseases caused by ferroptosis