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In addition to its principal activity in islet cells, ghrelin inhibits gastric secretion and gastrointestinal motility, delays gastric emptying, increases satiety and decreases food intake in gastrointestinal tissues (Brubaker and Drucker, 2002)

Paying attention to the flavors and textures of food can lead to improved satisfaction and reduced overeating, as individuals learn to better listen to their hunger and fullness cues

Moreover, the overexpression of COX-2 is often closely associated with chemotherapy resistance and immune escape processes in tumors, suggesting that COX-2 is an attractive therapeutic target in tumors (107)

We observed evidence indicating a protective causal effect of GLP-1RAs on ED risk