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People who are pregnant or have certain medical conditions, such as heart or liver concerns, should get medical clearance first

Contact your GP if you experience: Unexpected symptoms after starting B12 supplementation, including persistent skin reactions, gastrointestinal disturbance, or mild allergic manifestations Neurological symptoms such as significant tingling, numbness, weakness, or balance problemsthese may indicate B12 deficiency paradoxically, or alternative neurological conditions requiring assessment Unexplained fatigue or malaise that develops or worsens despite supplementation Concerns about medication interactions , particularly if taking metformin, proton pump inhibitors, or other medications affecting B12 metabolism [2] [4] Seek emergency medical attention (call 999) if you develop signs of a severe allergic reaction following B12 injection, including facial swelling, difficulty breathing, or widespread urticaria

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Sabrina Strickland, MD Orthopedic Surgeon, Hospital for Special Surgery Last reviewed: April 30, 2026 Quick Summary Some meniscus tears can heal without surgery, particularly small peripheral tears in well-vascularized red-zone tissue and degenerative tears in older patients without mechanical symptoms