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56.4, 112.8 or 225.6 mol /kg/day for 14 days) had congruent protective effects against CIR-induced damage and inflammation (110, 111)

Acute Side Effects (Dose-Dependent) These side effects occur within minutes to hours of each injection and are directly related to dose

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Pomegranate peel extract (PPE), a strong antioxidant, prevented Amikacin-caused ototoxicity in BALB/c mice through the modulation of the MAPK/FoxO3a signaling pathway within the cochlea