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When the MCD enzyme is defective, it can lead to abnormal levels of malonyl CoA, which in turn can impact brain CPT1 and contribute to abnormal brain development
Mild, transient fluid retention/edema and joint or muscle pain, each reported more often on MK-677 than placebo in the same trial, linked to elevated GH and IGF-1
Im pretty sure neither Novo Nordisk (the company behind Ozempic and Wegovy) or Eli Lilly (the manufacturer of Mounjaro and Zepbound) would object to all of us having at least one indication for taking these drugs
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