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This represents approximately 3-fold improved local delivery and demonstrates that formulation significantly impacts outcomes
Prescribers can adjust hydroquinone beyond the commercial 4% ceiling (up to 8% for refractory cases), swap the steroid component based on patient sensitivity, add tranexamic acid or cysteamine for resistant pigmentation, and choose vehicle bases optimized for different skin types and climates
Le Dr Corey L
Upon recognition of LPS, these caspases cleave GSDMD, leading to membrane pore formation and pyroptosis, similar to the classical pathway
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