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These are mechanistic observations within experimental systems, not claims about human physiology

staff at the Mass Spectrometry Resource Laboratory in the Center for Advanced Research Technologies (CART) and the Histology, Biochemistry, and Molecular Imaging (HBMI) Core at the Center for Musculoskeletal Research (CMSR) at URMC, the Proteomics/Metabolomics Core at Moffitt Cancer Center, which is funded in part by Moffitts Cancer Center Support Grant (P30CA076292), and University of Chicago Metabolomics Platform (RRID: SCR_022932)

Current IGF1 used in the clinic not only lacks the e-peptide but is also glycosylated, a less active form

It may interfere with chemotherapy drugs or decrease the efficacy of certain antipsychotics