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In aesthetic medicine, it is increasingly used: After microneedling procedures to accelerate recovery and enhance collagen induction Post laser resurfacing to support skin barrier restoration and reduce inflammation After chemical peels to minimize downtime and support reepithelialization In post-surgical recovery protocols to support soft tissue healing Citation: Pickart L, Vasquez-Soltero JM, Margolina A

No study has compared injecting near an injury against injecting elsewhere for these compounds "inject near the injury" is a reasonable, low-cost default, but it is practitioner convention, not an evidence-backed advantage

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5-Amino-1MQ is a small-molecule compound and selective inhibitor of NNMT (Nicotinamide N-methyltransferase), an enzyme involved in regulating NAD+ metabolism and one-carbon pathway signalling