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The ATP synthase beta subunit, a mitochondrial enzyme involved in redox regulation, associates with FUS, inducing the mitochondrial UPR in cellular and transgenic Drosophila models of ALS (Deng et al., 2018)
In adults with obesity, along with diet and exercise, Nausea was generally transient 4 Most occurrences of nausea did not lead to permanent discontinuation of Wegovy HD STEP UP: Reported nausea (median duration 6 days) In STEP UP, nausea was reported in all treatment arms and was most prevalent during the dose-escalation period 4 Nausea was not prospectively measured at each patient visit in clinical trials
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