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Plotting and mapping the changes in CSPs when bound with 6 M 1907 compared to DMSO control demonstrated that 1907 was able to induce CSP differences primarily in helix 23, specifically residues: M953, K955, E956, L959, R962, T963, L990, L994, G995 (Fig
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This ingredient is a known EU allergen and may sensitize the skin
Dose selection in the research literature varies with the application: musculoskeletal-injury studies commonly report 200250 g twice daily near the affected site, while gastrointestinal-focused protocols use 250500 g once or twice daily, subcutaneously
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