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In the SURPASS-2 trial, 15 mg tirzepatide reduced HbA1c by 2.58% compared to 1.86% with semaglutide 1 mg [2]
Acneiform reactions The most common cutaneous reaction with EGFR inhibitors is a widespread papulopustular acneiform eruption consisting of erythematous follicle-based papules and pustules without comedones
Weight Loss Efficacy# Head-to-Head: STEP 8 Trial# The STEP 8 trial (Rubino et al., JAMA 2022) directly compared semaglutide 2.4 mg weekly to liraglutide 3.0 mg daily in 338 adults with overweight or obesity without diabetes over 68 weeks
For a 200-pound woman, this translates to 10-30 pounds of loss
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