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Treatment can continue beyond that point if its working, in line with the recognition of obesity as a chronic condition that may need long-term care
do not expect immediate results on day one
Here we report the engineering and preclinical development of a bimodal molecule that integrates NMDA receptor antagonism with glucagon-like peptide-1 (GLP-1) receptor agonism to effectively reverse obesity, hyperglycaemia and dyslipidaemia in rodent models of metabolic disease
Patients who build strong lifestyle habits during initial treatment tend to need lower maintenance doses and report better quality of life
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