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J Neurosci 23:59285935 Aureli T, Di Cocco ME, Puccetti C, Ricciolini R, Scalibastri M, Miccheli A, Manetti C, Conti F (1998) Acetyl-L-carnitine modulates glucose metabolism and stimulates glycogen synthesis in rat brain

Results may take time, usually weeks or months

Potent anti-proliferative actions of a non-diuretic glucosamine derivative of ethacrynic acid

Clinically, this would lead to unpredictable results, with the day-to-day efficacy of the supplement varying wildly with the food consumed by the patient